OmegaFold
HeliXon Protein
Single-sequence structure prediction using a protein language model plus geometry-inspired transformer. First MSA-free method to approach AF2 accuracy.
Best For
Orphan and metagenomic protein structure prediction
License
Open Source (check repo)
Strengths
- +No MSA needed
- +Approaches AF2 accuracy
Limitations
- −Monomers only
- −4096 aa GPU limit
- −No active development since 2023
R&D Pipeline Coverage
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